Covid-19 Live Updates: Vaccine Shipments Start to Roll in the U.S. The first doses of the Pfizer-BioNTech vaccine left a facility in Michigan early Sunday, with UPS and FedEx teaming up to ship them to all 50 states for distribution. nytimes

The first of nearly three million doses of the first Covid-19 vaccine were packed in dry ice and put on trucks at a Pfizer plant in Kalamazoo, Mich., on Sunday morning, destined for hundreds of distribution centers in all 50 states, the most ambitious vaccination campaign in American history.

Coronavirus Is Surging: How Severe Is Your State's Outbreak? View NPR's maps and graphics to see where COVID-19 is hitting hardest in the U.S., which state outbreaks are growing and which are leveling off. NPR.org

More than 15 million people in the U.S. have had confirmed coronavirus infections and more than 280,000 have died of COVID-19. Tens of thousands of new cases are reported daily nationwide. In the graphics (attached) , explore the trends in your state.

U.S. government buys another 100 million doses of Moderna vaccine The expanded order would ensure continuous vaccine delivery through the end of June 2021, at a total cost of $3.2 billion, the Trump administration said. Sarah Owermohle POLITICO

The United States will buy 100 million additional shots of Moderna’s Covid-19 vaccine — doubling its initial order of the vaccine, which the FDA is expected to authorize later this month.

With new coronavirus cases and deaths continuing to emerge at record levels, the United States is poised to begin a lengthy vaccination campaign.

The first shipments of Pfizer-BioNTech and Moderna vaccine will not be enough to inoculate even just the medical workers and nursing home residents at the top of the waiting list. But after federal regulators granted emergency authorization for the Pfizer vaccine, millions of doses were expected to be shipped across the country, a small but tangible step toward ending the pandemic.

By design, the vaccine rollout will be a patchwork. Though federal regulators are responsible for deciding when a vaccine can be safely used, it is largely up to the states to determine how to deploy the doses they receive. Recipients of both vaccines will need two doses administered weeks apart. Distribution is meant to be based on adult population estimates.

The darkest hour for America is still to come, experts say. What we do next is key. If Americans do not change their behavior quickly, experts warn, the weeks and months ahead will be filled with more death and despair, packed hospitals and unemployment lines. Daniel Arkin NBCNews

How was a microscopic virus able to bring the world’s richest and most powerful country to its knees?

The Latest: California officials urge citizens to stay home MANHATTAN BEACH, Calif. — California health officials are urging the state’s residents to stay home as much as possible because of a coronavirus surge taxing the state’s hospitals. But the... AP NEWS

— U.S. daily coronavirus deaths top 3,000, more tha n 9/11 or Pearl Harbor